Ethylpropyltryptamine

Ethylpropyltryptamine (also known as EPT) is a lesser-known psychedelic drug. It is a member of the tryptamine class. Very little data exists about the pharmacological properties, metabolism, and toxicity of EPT.

Chemistry

Ethylpropyltryptamine, or EPT, is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. EPT is substituted at R4 of its indole heterocycle with an ethyl group. It also contains two propyl chains bound to the terminal amine RN of its tryptamine backbone (EPT).

Pharmacology

Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other psychedelic tryptamines. EPT likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from EPT’s efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Effects

The effects of EPT are usually compared to those of other psychedelic tryptamines like DMT and Psilocin. These effects include geometric visual hallucinations, time distortion, enhanced introspection, and ego loss. However, EPT is often described as being less intense than DMT and Psilocin with a shorter duration.

Toxicity and harm potential

As with all psychedelics, EPT has the potential to be harmful if used irresponsibly. It is strongly recommended that one use harm reduction practices if using this substance.

Legal status

The legal status of EPT varies by country. It is not controlled in the United States, but it could potentially be considered an analogue of DMT under the Federal Analogue Act.

See also

• Tryptamine
• Psychedelic drug
• DMT
• Psilocin

References

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