External limiting membrane

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External limiting membrane
Gray881.png
Section of retina. (Membrana limitans externa labeled at right, third from the top.)
Gray882.png
Plan of retinal neurons. (Membrana limitans externa labeled at left, second from the bottom.)
Details
Identifiers
Latinmembrana limitans externa
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FMA{{#property:P1402}}
Anatomical terminology
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The External limiting membrane (ELM) is a layer of the retina in the eye. It is not a true membrane, but a series of junctions that form a barrier within the retina.

Structure[edit | edit source]

The ELM is located towards the outer surface of the retina, between the inner nuclear layer and the outer plexiform layer. It is composed of a series of zonula adherens junctions between Müller cells and the photoreceptor cells.

Function[edit | edit source]

The ELM acts as a barrier and regulator between the neural retina and the retinal pigment epithelium. It plays a crucial role in maintaining the structural and functional integrity of the retina.

Clinical significance[edit | edit source]

Damage or disruption to the ELM can lead to various retinal diseases, including macular degeneration and retinitis pigmentosa.

See also[edit | edit source]

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This code will create an article with an infobox at the top, including two images from Wikimedia Commons. The article is divided into sections for the structure, function, and clinical significance of the ELM, and includes internal links to related articles. The article is categorized under "Human eye anatomy" and "Retina".

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Contributors: Prab R. Tumpati, MD