FM (chemotherapy)

Chemical structure of Fluorouracil, one of the components of FM chemotherapy

FM chemotherapy is a chemotherapy regimen that is used in the treatment of various types of cancer. The regimen consists of two drugs: Fluorouracil (F) and Mitomycin (M).

Fluorouracil

Fluorouracil is a pyrimidine analog that inhibits the enzyme thymidylate synthase, which is necessary for DNA synthesis. By inhibiting this enzyme, fluorouracil disrupts the growth of cancer cells and leads to their death.

Mitomycin

Mitomycin is an antibiotic that also has antineoplastic properties. It works by cross-linking DNA, which prevents the cancer cells from replicating and causes them to die.

Use in cancer treatment

FM chemotherapy is used in the treatment of various types of cancer, including gastrointestinal cancer, pancreatic cancer, and breast cancer. The specific regimen and dosage may vary depending on the type and stage of cancer, as well as the patient's overall health.

Side effects

Like all chemotherapy regimens, FM chemotherapy can cause side effects. These may include nausea, vomiting, diarrhea, fatigue, and hair loss. More serious side effects can include neutropenia, thrombocytopenia, and anemia.

See also

• Chemotherapy
• Cancer
• Fluorouracil
• Mitomycin