Faxeladol

Faxeladol is a pharmacological agent that belongs to the class of opioid analgesics. It is a synthetic opioid that is used for the management of moderate to severe pain. Faxeladol is a prodrug of oxycodone, meaning it is metabolically converted into oxycodone in the body.

Pharmacology

Faxeladol is a prodrug of oxycodone, which means it is inactive until it is metabolized in the body. The conversion of faxeladol to oxycodone occurs primarily in the liver through the action of the enzyme cytochrome P450 3A4 (CYP3A4). Once converted to oxycodone, it exerts its analgesic effects by binding to the mu-opioid receptor in the central nervous system.

Clinical Use

Faxeladol is used for the management of moderate to severe pain. It is typically used in situations where non-opioid analgesics are not effective. The drug is usually administered orally, and its effects can last for up to 12 hours.

Side Effects

Like other opioids, faxeladol can cause a range of side effects. These can include nausea, vomiting, constipation, dizziness, and sedation. More serious side effects can include respiratory depression, which can be life-threatening if not managed properly.

Contraindications

Faxeladol is contraindicated in patients with known hypersensitivity to oxycodone or any other ingredients in the product. It is also contraindicated in patients with severe respiratory depression, severe bronchial asthma, or paralytic ileus.

Interactions

Faxeladol can interact with a number of other medications. These include other opioids, sedatives, hypnotics, tranquilizers, and alcohol. These interactions can increase the risk of respiratory depression, sedation, and death.

See Also

• Opioid
• Oxycodone
• Prodrug
• Cytochrome P450
• Mu-opioid receptor