Fenofibrate/pravastatin

Fenofibrate/Pravastatin is a combination medication used in the treatment of high cholesterol. It contains two active ingredients: Fenofibrate, a fibrate, and Pravastatin, a statin. Both of these drugs work in different ways to lower cholesterol levels in the body.

Etymology

The term "Fenofibrate" is derived from the chemical name of the drug, which is "2-[4-(4-chlorobenzoyl) phenoxy]-2-methylpropanoic acid, 1-methylethyl ester". The term "Pravastatin" is derived from the chemical name "Pravastatin sodium".

Mechanism of Action

Fenofibrate works by increasing the natural substance (enzyme) that breaks down fats in the blood. Pravastatin works by reducing the amount of cholesterol made by the liver. In turn, the liver is able to process more of the cholesterol in the blood, lowering the total amount of cholesterol in the body.

Side Effects

Common side effects of Fenofibrate/Pravastatin include headache, heartburn, and nausea. Serious side effects can include muscle pain or weakness, dark colored urine, and yellowing of the skin or eyes (jaundice).

Related Terms

• Hypercholesterolemia: A condition characterized by very high levels of cholesterol in the blood.
• Statin: A class of drugs used to lower blood levels of cholesterol.
• Fibrate: A class of drugs used to lower levels of fats (lipids) in the blood, such as triglycerides.

See Also

• Lipid-lowering agent
• Cardiovascular disease