Fenoverine

Fenoverine is a spasmolytic agent that is used in the treatment of various gastrointestinal disorders. It is a synthetic compound that belongs to the class of drugs known as antispasmodics. Fenoverine acts by relaxing the smooth muscles of the gastrointestinal tract, thereby relieving symptoms such as abdominal pain, bloating, and discomfort.

Pharmacology

Fenoverine is a non-selective calcium channel blocker, which means it inhibits the influx of calcium ions into smooth muscle cells. This action results in the relaxation of these muscles, reducing spasms and associated symptoms. Fenoverine also has an anticholinergic effect, which contributes to its spasmolytic action.

Clinical Use

Fenoverine is used in the management of Irritable Bowel Syndrome (IBS) and other functional gastrointestinal disorders. It is effective in relieving symptoms such as abdominal pain, bloating, and discomfort. Fenoverine is usually well-tolerated, with few side effects. The most common side effects include dry mouth, blurred vision, and constipation.

Dosage and Administration

Fenoverine is typically administered orally, in the form of capsules. The usual dosage is one capsule three times a day, taken before meals. The duration of treatment depends on the severity of symptoms and the individual patient's response to therapy.

Contraindications and Precautions

Fenoverine is contraindicated in patients with known hypersensitivity to the drug. It should be used with caution in patients with glaucoma, urinary retention, or prostatic hypertrophy due to its anticholinergic effects.

Interactions

Fenoverine may interact with other drugs, particularly those with anticholinergic effects. Concurrent use with such drugs may increase the risk of side effects.