Ferm domain containing 4b
Ferm domain containing 4b (also known as FRMD4B) is a protein that in humans is encoded by the FRMD4B gene. The protein encoded by this gene is a member of the FERM family of proteins, which are involved in a variety of cellular processes including cell adhesion, cytoskeletal organization, and signal transduction.
Structure[edit | edit source]
The FRMD4B protein contains a FERM domain, which is a protein domain that is found in a variety of proteins involved in cellular processes such as cell adhesion, cytoskeletal organization, and signal transduction. The FERM domain is a three-lobed structure that binds to the plasma membrane and other intracellular targets.
Function[edit | edit source]
The exact function of the FRMD4B protein is not fully understood. However, it is known to play a role in cell adhesion and cytoskeletal organization. It is also thought to be involved in signal transduction, a process that allows cells to respond to signals from their environment.
Clinical significance[edit | edit source]
Mutations in the FRMD4B gene have been associated with a variety of diseases, including cancer. In particular, overexpression of the FRMD4B protein has been observed in several types of cancer, suggesting that it may play a role in cancer development and progression.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD