Fertirelin

Fertirelin is a synthetic gonadotropin-releasing hormone (GnRH) used in veterinary medicine. It is primarily used in cattle and horses to induce ovulation and treat certain reproductive disorders.

Chemical Structure and Function

Fertirelin is a decapeptide, meaning it is composed of ten amino acids. Its chemical structure is similar to that of natural GnRH, but it has a longer half-life and is more potent. Fertirelin works by stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones then stimulate the ovaries to produce eggs and the testes to produce sperm.

Uses in Veterinary Medicine

In cattle, fertirelin is used to treat cystic ovarian disease and induce ovulation. It is also used in horses to induce ovulation and treat certain reproductive disorders. Fertirelin is administered by injection and the dosage varies depending on the species and the condition being treated.

Side Effects and Precautions

As with any medication, fertirelin can cause side effects. These may include injection site reactions, allergic reactions, and changes in reproductive behavior. Fertirelin should not be used in animals with known hypersensitivity to GnRH or its analogs. It should also be used with caution in animals with liver or kidney disease.

Regulation and Availability

Fertirelin is a prescription medication and is regulated by the Food and Drug Administration (FDA) in the United States. It is available in many countries around the world, but the availability may vary depending on the country's regulatory policies.

See Also

• Gonadotropin-releasing hormone
• Luteinizing hormone
• Follicle-stimulating hormone
• Cystic ovarian disease