Filgotinib maleate

Filgotinib Maleate is a Janus kinase inhibitor used in the treatment of rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is a selective inhibitor of Janus kinase 1 (JAK1), a type of enzyme that plays a crucial role in the signaling pathways for various cytokines and growth factors involved in inflammation and immune response.

Mechanism of Action

Filgotinib Maleate works by selectively inhibiting JAK1, which is involved in the signaling pathway for various cytokines and growth factors. By inhibiting JAK1, Filgotinib Maleate can reduce inflammation and other symptoms associated with autoimmune diseases.

Uses

Filgotinib Maleate is used in the treatment of several autoimmune diseases, including:

• Rheumatoid arthritis: Filgotinib Maleate can reduce inflammation and pain in the joints, improving mobility and quality of life for patients with rheumatoid arthritis.
• Ulcerative colitis: By reducing inflammation in the colon, Filgotinib Maleate can alleviate symptoms of ulcerative colitis such as abdominal pain and diarrhea.
• Crohn's disease: Filgotinib Maleate can help manage the symptoms of Crohn's disease, which include abdominal pain, diarrhea, and weight loss.

Side Effects

Like all medications, Filgotinib Maleate can cause side effects. These may include:

• Nausea
• Diarrhea
• Fatigue
• Headache
• Abdominal pain

Patients should consult their healthcare provider if they experience any severe or persistent side effects.

See Also

• Janus kinase inhibitor
• Rheumatoid arthritis
• Ulcerative colitis
• Crohn's disease