Floctafenine

Floctafenine is a non-steroidal anti-inflammatory drug (NSAID) that is primarily used in the treatment of pain and inflammation associated with various medical conditions. It is a member of the fenamate group of NSAIDs, and its anti-inflammatory and analgesic properties are thought to be related to its ability to inhibit the synthesis of prostaglandins, substances that play a key role in mediating inflammation and pain.

Pharmacology[edit | edit source]

Floctafenine works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. By blocking the action of COX, floctafenine reduces the levels of prostaglandins, thereby reducing inflammation and pain.

Clinical Use[edit | edit source]

Floctafenine is used to relieve pain and inflammation in a variety of conditions, including rheumatoid arthritis, osteoarthritis, and acute gout. It can also be used to alleviate post-operative pain and to treat other conditions as determined by a healthcare provider.

Side Effects[edit | edit source]

Like other NSAIDs, floctafenine can cause a range of side effects. These may include gastrointestinal problems such as stomach ulcers and bleeding, kidney problems, and an increased risk of heart attack or stroke. It is important for patients to discuss these risks with their healthcare provider before starting treatment with floctafenine.

Contraindications[edit | edit source]

Floctafenine should not be used by individuals with a history of allergic reaction to NSAIDs, or by those with severe heart failure, liver disease, or kidney disease. It should also be used with caution in individuals with a history of stomach ulcers or bleeding, or in those taking other medications that can increase the risk of these conditions.