Flurithromycin

Flurithromycin is a macrolide antibiotic. It is a fluorinated derivative of erythromycin.

Chemistry

Flurithromycin is a semi-synthetic macrolide antibiotic. It is a fluorinated derivative of erythromycin, which means it has a fluorine atom incorporated into its molecular structure. This modification is believed to enhance the antibiotic's effectiveness.

Pharmacology

Like other macrolide antibiotics, flurithromycin works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thereby preventing the translocation of peptides.

Clinical Use

Flurithromycin is used in the treatment of various bacterial infections, including respiratory tract infections, skin infections, and sexually transmitted infections. It is particularly effective against gram-positive bacteria, but also has activity against some gram-negative bacteria.

Side Effects

The most common side effects of flurithromycin are gastrointestinal disturbances, including nausea, vomiting, and diarrhea. Less common side effects include rash, liver dysfunction, and hearing loss.

See Also

• Macrolide
• Erythromycin
• Antibiotic

Flurithromycin Resources
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