Freeze dry

From WikiMD's Wellness Encyclopedia

Freeze-drying (also known as lyophilization or cryodesiccation) is a low temperature dehydration process that involves freezing the product, lowering pressure, then removing the ice by sublimation. This is in contrast to dehydration by most conventional methods that evaporate water using heat.

Process[edit | edit source]

Freeze-drying works by freezing the material and then reducing the surrounding pressure to allow the frozen water in the material to sublimate directly from the solid phase to the gas phase. The process consists of three stages: pre-freezing, primary drying, and secondary drying.

Pre-freezing[edit | edit source]

The preparation stage of freeze-drying, pre-freezing, involves cooling the material below its triple point. This ensures that sublimation rather than melting will occur in the following steps.

Primary drying[edit | edit source]

During the primary drying phase, the pressure is lowered and enough heat is supplied to the material for the water to sublimate. The amount of heat necessary can be calculated using the sublimation heat (the heat of sublimation) and the rate of sublimation.

Secondary drying[edit | edit source]

The secondary drying phase aims to remove any unfrozen water molecules, since the ice was removed in the primary drying phase. This part of the freeze-drying process is governed by the principles of desorption.

Applications[edit | edit source]

Freeze-drying is used in a variety of sectors, from pharmaceutical companies to the food industry. In the pharmaceutical industry, it is used to dry vaccines, antibiotics, and other drugs. In the food industry, it is used to preserve food, increase its shelf life, and make it more convenient for transport.

Advantages and Disadvantages[edit | edit source]

Freeze-drying has many advantages over other drying methods. It maintains the physical structure of the material, and preserves the nutritional content and flavors of the food. However, it is a complex and expensive process, which can be a disadvantage for some applications.

See also[edit | edit source]


This industrial process related article is a stub. You can help WikiMD by expanding it.

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD