Friability

From WikiMD's Wellnesspedia

Friability (pronounced fry-uh-BIL-uh-tee) refers to the quality of a solid substance to disintegrate into smaller pieces with minimal effort. The antonym for friable is indurate.

Characteristics and Implications[edit | edit source]

Materials deemed hazardous, like asbestos or crystalline silica, are frequently classified as friable when they can easily shed small particles. This makes them respirable, allowing them to be inhaled into human lungs, which could result in health risks.

While tougher materials such as concrete might be mechanically ground into fine mineral dust, they aren't typically deemed friable due to the challenge involved in severing their chemical bonds mechanically. Substances like polyurethane foams may exhibit increased friability upon exposure to ultraviolet radiation found in sunlight.

The term "friabile" also has a psychological context, describing personalities that exhibit intense emotional reactions to minor stimuli.

Examples[edit | edit source]

Friable substances are those that easily disintegrate into fibers or finer particles with minor pressure or friction. Such substances include:

Geological Usage[edit | edit source]

In the domain of soft-rock geology, the terms friable and indurated are frequently utilized, especially when discussing sandstones, mudstones, and shales, to describe the cohesion or cementation of the rock.

Medical Usage[edit | edit source]

In medicine, friability describes tumors that can be effortlessly torn, indicating a greater risk of malignancy and metastasis. Examples include:

Pharmaceutical Usage[edit | edit source]

Friability testing is a lab technique utilized in the pharmaceutical sector to determine the potential of a tablet to fragment into tinier particles during transit. The procedure involves subjecting a sample of tablets to repeated drops over a set duration, using a rotating wheel equipped with a baffle. Subsequently, the tablets are inspected for any damages, and the percentage mass loss due to chipping is calculated. Typical specifications permit a certain percentage loss from chipping and disallow completely broken tablets.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD