GR-55562
Chemical compound
GR-55562 is a chemical compound that acts as a selective antagonist of the 5-HT1B receptor, a subtype of the serotonin receptor. It is primarily used in scientific research to study the role of the 5-HT1B receptor in various physiological and pathological processes.
Chemical Properties[edit | edit source]
GR-55562 is a synthetic compound with a complex chemical structure. It is characterized by its high affinity for the 5-HT1B receptor, which allows it to effectively block the action of serotonin at this receptor site. The chemical structure of GR-55562 includes several functional groups that contribute to its binding affinity and selectivity.
Pharmacology[edit | edit source]
As a 5-HT1B receptor antagonist, GR-55562 inhibits the action of serotonin, a neurotransmitter involved in the regulation of mood, appetite, and other functions. By blocking the 5-HT1B receptor, GR-55562 can alter the effects of serotonin in the brain and other tissues, making it a valuable tool for research into the serotonergic system.
Mechanism of Action[edit | edit source]
GR-55562 binds to the 5-HT1B receptor, preventing serotonin from activating this receptor. This blockade can lead to changes in neurotransmitter release and modulation of neuronal activity. The 5-HT1B receptor is involved in the regulation of dopamine and norepinephrine release, and its antagonism by GR-55562 can influence these neurotransmitter systems.
Research Applications[edit | edit source]
GR-55562 is used in research to explore the role of the 5-HT1B receptor in various conditions, including depression, anxiety, and migraine. It is also used to study the receptor's involvement in cardiovascular function and pain perception. By understanding how GR-55562 affects these processes, researchers can gain insights into potential therapeutic targets for related disorders.
Safety and Handling[edit | edit source]
As with many research chemicals, GR-55562 should be handled with care in a laboratory setting. Appropriate safety measures, including the use of personal protective equipment, should be followed to minimize exposure and potential health risks.
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
