GTF3C1
GTF3C1 is a gene that encodes a protein involved in RNA polymerase III transcription. It is a part of the General Transcription Factor IIIC group, which is a complex necessary for transcription of genes by RNA polymerase III. The GTF3C1 protein is a subunit of this complex and plays a crucial role in the initiation of transcription.
Function[edit | edit source]
The GTF3C1 gene provides instructions for making a protein that is a part of a larger complex known as the General Transcription Factor IIIC. This complex is involved in the initiation of transcription, a process that involves copying DNA into RNA. The GTF3C1 protein specifically helps to bind the complex to DNA and initiate transcription.
Clinical Significance[edit | edit source]
Mutations in the GTF3C1 gene have been associated with various diseases. For instance, some studies have suggested a link between alterations in this gene and cancer. However, more research is needed to fully understand the role of GTF3C1 in disease development and progression.
See Also[edit | edit source]
References[edit | edit source]
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