Gas gangrene
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Gas gangrene | |
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Synonyms | Clostridial myonecrosis |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Severe pain, swelling, fever, skin discoloration, blisters with foul-smelling discharge |
Complications | Sepsis, shock, organ failure |
Onset | Rapid, within hours to days after injury |
Duration | Variable, can be fatal within 48 hours if untreated |
Types | N/A |
Causes | Clostridium perfringens, Clostridium septicum, other Clostridium species |
Risks | Trauma, surgery, diabetes mellitus, peripheral vascular disease |
Diagnosis | Clinical diagnosis, imaging, Gram stain, culture |
Differential diagnosis | Necrotizing fasciitis, cellulitis, deep vein thrombosis |
Prevention | Proper wound care, prophylactic antibiotics in high-risk surgeries |
Treatment | Surgical debridement, antibiotics, hyperbaric oxygen therapy |
Medication | N/A |
Prognosis | Poor if untreated; better with early intervention |
Frequency | Rare |
Deaths | N/A |
Gas gangrene is a bacterial infection that produces gas in tissues in gangrene. This deadly form of gangrene usually is caused by Clostridium perfringens bacteria. It is a medical emergency.
Causes[edit | edit source]
Gas gangrene is caused by a bacterial infection from the group of bacteria known as Clostridium. The bacteria produce gas and toxins, and are able to survive in conditions with low oxygen levels. The most common cause of gas gangrene is Clostridium perfringens, but other types of clostridium can also cause the condition.
Symptoms[edit | edit source]
The symptoms of gas gangrene include severe pain in the affected area, swelling, and the production of gas, which can be felt under the skin. The skin may become pale and then turn gray or purplish red. The patient may also experience fever, sweating, and increased heart rate.
Diagnosis[edit | edit source]
Gas gangrene is diagnosed through a physical examination and medical history. The doctor may also order imaging tests such as an X-ray or MRI to look for gas in the tissues. A sample of tissue or fluid may be taken from the affected area and tested for the presence of clostridium bacteria.
Treatment[edit | edit source]
Treatment for gas gangrene includes antibiotics to kill the bacteria and surgery to remove the dead tissue. In severe cases, amputation of the affected limb may be necessary. Hyperbaric oxygen therapy, which involves breathing pure oxygen in a pressurized room, may also be used to increase the amount of oxygen in the blood and help kill the bacteria.
Prevention[edit | edit source]
Prevention of gas gangrene involves proper wound care, especially for deep wounds and those caused by surgery or trauma. This includes cleaning the wound thoroughly and keeping it clean and dry.
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Contributors: Kondreddy Naveen, Prab R. Tumpati, MD