Gemeprost
Gemeprost is a synthetic analogue of prostaglandin E1 (PGE1) that is used as a medication. It is an abortifacient, which means it can induce abortion, and it is also used in the treatment of cervical ripening before surgical abortion.
Medical Uses[edit | edit source]
Gemeprost is used in medicine for two main purposes. The first is as an abortifacient, in combination with mifepristone, for the termination of pregnancy up to 63 days gestation. The second use is for the preparation of the cervix for surgical abortion.
Mechanism of Action[edit | edit source]
Gemeprost works by interacting with prostaglandin E receptors. This interaction leads to a series of events that result in the softening, dilation, and effacement of the cervix, which are necessary for childbirth and abortion. In addition, gemeprost stimulates the contraction of the uterus, which helps to expel the pregnancy.
Side Effects[edit | edit source]
The most common side effects of gemeprost include nausea, vomiting, diarrhea, and abdominal pain. Other side effects can include fever, chills, headache, and dizziness. In rare cases, gemeprost can cause severe allergic reactions.
Contraindications[edit | edit source]
Gemeprost is contraindicated in patients with known hypersensitivity to prostaglandins. It should not be used in patients with asthma, glaucoma, or cardiovascular disease without careful consideration of the risks and benefits.
See Also[edit | edit source]
Gemeprost Resources | ||
---|---|---|
|
|
|
Find a healthcare provider anywhere in the world quickly and easily!
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
WikiMD is the world's largest, free medical and wellness encyclopedia edited only by professionals. Advertise!
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Admin, Prab R. Tumpati, MD