Gritstone bio
Gritstone bio is a biotechnology company focused on developing innovative immunotherapies for the treatment of cancer and infectious diseases. The company leverages its proprietary technology platforms to identify and target specific antigens that can stimulate the immune system to attack diseased cells.
History[edit | edit source]
Gritstone bio was founded in 2015 by a team of experts in immunotherapy, genomics, and bioinformatics. The company is headquartered in Emeryville, California. Since its inception, Gritstone bio has been dedicated to advancing the field of immunotherapy through rigorous scientific research and clinical development.
Technology Platforms[edit | edit source]
Gritstone bio utilizes two main technology platforms:
- EDGE™ Platform: This platform is designed to predict and identify tumor-specific neoantigens. Neoantigens are unique proteins that arise from mutations in cancer cells and can be targeted by the immune system.
- SLATE™ Platform: This platform focuses on the development of personalized cancer vaccines. By using the information from the EDGE™ platform, SLATE™ creates vaccines tailored to the unique neoantigens present in an individual’s tumor.
Pipeline[edit | edit source]
Gritstone bio's pipeline includes several product candidates in various stages of development:
- GRANITE™: A personalized immunotherapy for the treatment of solid tumors. GRANITE™ is designed to target multiple neoantigens identified in a patient's tumor.
- SLATE™: An off-the-shelf immunotherapy targeting shared neoantigens found in common tumor types.
- CORAL™: A program focused on developing vaccines for infectious diseases, including COVID-19.
Clinical Trials[edit | edit source]
Gritstone bio is actively conducting clinical trials to evaluate the safety and efficacy of its product candidates. These trials are essential for gaining regulatory approval and bringing new therapies to patients.
Collaborations[edit | edit source]
The company has established collaborations with leading academic institutions and pharmaceutical companies to advance its research and development efforts. These partnerships are crucial for accessing additional expertise and resources.
Leadership[edit | edit source]
Gritstone bio is led by a team of experienced professionals in the fields of biotechnology, immunotherapy, and business management. The leadership team is committed to driving the company's mission of transforming the treatment of cancer and infectious diseases.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
