Group C nerve fiber

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Medulla spinalis - Substantia grisea - English.svg

Group C nerve fiber refers to a type of nerve fiber that is unmyelinated and has a small diameter. These fibers are part of the peripheral nervous system and are responsible for transmitting various types of sensory information, including pain and temperature sensations.

Structure[edit | edit source]

Group C nerve fibers are characterized by their lack of myelin, a fatty substance that typically surrounds and insulates other types of nerve fibers, such as Group A and Group B nerve fibers. The absence of myelin in Group C fibers results in slower transmission speeds for nerve impulses. These fibers have a diameter ranging from 0.2 to 1.5 micrometers.

Function[edit | edit source]

Group C nerve fibers play a crucial role in the transmission of pain and temperature sensations. They are involved in the conduction of slow, chronic pain signals, often described as dull or aching pain. Additionally, these fibers are responsible for transmitting information related to itch and certain types of touch.

Pathways[edit | edit source]

The sensory information carried by Group C nerve fibers is transmitted to the spinal cord and then relayed to the brain for processing. These fibers enter the spinal cord through the dorsal root ganglion and synapse in the dorsal horn of the spinal cord. From there, the signals are transmitted to higher brain centers via the spinothalamic tract.

Clinical Significance[edit | edit source]

Damage or dysfunction of Group C nerve fibers can result in various medical conditions, including neuropathic pain, chronic pain, and certain types of peripheral neuropathy. Understanding the role of these fibers in pain transmission is essential for developing effective pain management strategies.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD