Gumma (pathology)

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Gumma (pathology)

A gumma is a soft, non-cancerous growth resulting from the tertiary stage of syphilis, which is a sexually transmitted infection caused by the bacterium Treponema pallidum. Gummata can develop on any organ of the body, including the skin, bones, and internal organs, and can cause severe damage if left untreated.

Causes[edit | edit source]

Gumma is caused by the bacterium Treponema pallidum, which is responsible for syphilis. The bacterium is usually transmitted through sexual contact, but can also be passed from mother to child during pregnancy (congenital syphilis).

Symptoms[edit | edit source]

The symptoms of a gumma can vary depending on its location. If it develops on the skin, it may appear as a firm, painless lump that slowly erodes over time. If it develops on an internal organ, it can cause a variety of symptoms depending on the organ affected.

Diagnosis[edit | edit source]

Diagnosis of a gumma typically involves a physical examination and a review of the patient's medical history. Blood tests may also be performed to confirm the presence of Treponema pallidum.

Treatment[edit | edit source]

Treatment for a gumma typically involves antibiotics to kill the Treponema pallidum bacterium. In some cases, surgery may be required to remove the gumma.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD