HOT-17

HOT-17 is a psychedelic drug and a member of the phenethylamine family. It is related to the more well-known compounds 2C-E and DOB. HOT-17 was first synthesized and studied by the team led by Alexander Shulgin.

Chemistry

HOT-17, or 2,5-dimethoxy-4-(β-isohexyl)-phenethylamine, is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. HOT-17 shares this phenethylamine structure with other psychedelic drugs like mescaline and 2C-B.

Pharmacology

The pharmacological mechanisms of HOT-17 are not well understood. It is believed to act as a 5-HT2A receptor agonist, similar to other psychedelic phenethylamines. However, the exact nature of its interactions with the 5-HT2A receptor and other potential targets is not known.

Effects

The effects of HOT-17 are largely unknown due to the lack of scientific research. Anecdotal reports suggest that it produces effects similar to other psychedelic phenethylamines, including open and closed-eye visuals, time distortion, enhanced introspection, and altered auditory and visual perception.

Legality

The legality of HOT-17 varies by country. In the United States, it is not specifically listed as a controlled substance, but it could potentially be considered an analog of DOB, which is a Schedule I drug under the Controlled Substances Act.

See also

• Phenethylamine
• Psychedelic drug
• Alexander Shulgin
• DOB
• 2C-E