HTN1

HTN1 is a gene that in humans is encoded by the HTN1 protein. It is a member of the histatin family of proteins, which are salivary proteins with antimicrobial activity against Candida albicans. The HTN1 gene is found on chromosome 4.

Function

The HTN1 gene encodes a member of the histatin family of proteins. Histatins are small proteins that are rich in histidine and are found in human saliva. They have antimicrobial activity, particularly against the fungus Candida albicans, which can cause oral thrush and other infections.

Clinical significance

Mutations in the HTN1 gene have been associated with increased susceptibility to oral candidiasis, a common fungal infection of the mouth. This suggests that the HTN1 protein plays an important role in the body's defense against fungal infections.

See also

• Histatin
• Candida albicans
• Oral candidiasis

External links

• HTN1 at the National Center for Biotechnology Information

HTN1 Resources
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