Haff

Haff disease is a rare syndrome characterized by rhabdomyolysis (breakdown of muscle tissue) after consuming certain types of fish. The disease was first described in 1924 in the vicinity of the Haff, a lagoon by the Baltic Sea near Königsberg, Germany (now Kaliningrad, Russia).

Symptoms

The symptoms of Haff disease typically occur within 24 hours of consuming the affected fish. They include:

• Chest pain
• Muscle pain
• Nausea
• Vomiting
• Shortness of breath
• Sweating
• Weakness

Causes

The exact cause of Haff disease is unknown, but it is believed to be related to a toxin in certain types of fish. The disease has been associated with the consumption of several species of fish, including:

• Buffalo fish
• Burbot
• Pike
• Eel
• Salmon

Diagnosis

Haff disease is diagnosed based on the patient's symptoms and history of fish consumption. Laboratory tests may show elevated levels of creatine kinase, a marker of muscle damage.

Treatment

Treatment for Haff disease is supportive and includes:

• Intravenous fluids
• Pain relief
• Monitoring of kidney function

Prevention

Prevention of Haff disease involves avoiding the consumption of fish known to be associated with the disease.

See also

• Foodborne illness
• Rhabdomyolysis
• Seafood poisoning

Haff Resources
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