Hemicholinium-3

Hemicholinium-3 (HC-3) is a neurotoxin which acts as an inhibitor of the choline transporter. It is often used in scientific research to reduce levels of acetylcholine in the brain.

Mechanism of Action

HC-3 works by blocking the high-affinity choline transporter (CHT), which is responsible for the uptake of choline into neurons. This prevents the synthesis of acetylcholine, a key neurotransmitter involved in many functions including muscle movement and memory.

Uses in Research

In research, HC-3 is used to study the role of acetylcholine in the brain. By inhibiting the production of acetylcholine, scientists can observe the effects of reduced acetylcholine levels on various brain functions.

Side Effects

As a neurotoxin, HC-3 can have serious side effects if not handled properly. These can include neurological damage and death. Therefore, it is important that HC-3 is used only under the supervision of trained professionals.

See Also

• Neurotoxin
• Choline transporter
• Acetylcholine

References

Hemicholinium-3 Resources
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