Henri-Alexandre Danlos
Henri-Alexandre Danlos (1844–1912) was a French physician and dermatologist known for his contributions to the study of connective tissue disorders. He is best known for his work on the condition now known as Ehlers-Danlos syndrome, which he described in collaboration with Danish dermatologist Edvard Ehlers.
Early Life and Education[edit | edit source]
Henri-Alexandre Danlos was born in 1844 in Paris, France. He pursued his medical education at the University of Paris, where he developed an interest in dermatology and connective tissue disorders.
Career[edit | edit source]
Danlos worked at several prominent hospitals in Paris, including the Hôpital Saint-Louis, which was renowned for its dermatology department. He conducted extensive research on various skin conditions and connective tissue disorders, contributing significantly to the field of dermatology.
Ehlers-Danlos Syndrome[edit | edit source]
In 1908, Danlos, along with Edvard Ehlers, described a group of patients with hyperelastic skin, hypermobile joints, and a tendency to bruise easily. This condition was later named Ehlers-Danlos syndrome in their honor. The syndrome is now known to encompass a group of genetic disorders affecting the collagen synthesis, leading to defects in the connective tissues.
Legacy[edit | edit source]
Henri-Alexandre Danlos' work laid the foundation for further research into connective tissue disorders. His contributions have had a lasting impact on the field of dermatology and the understanding of genetic disorders affecting the connective tissues.
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Contributors: Prab R. Tumpati, MD