Hopkins syndrome

From WikiMD's Wellness Encyclopedia

Hopkins Syndrome is a rare neurological disorder characterized by the sudden onset of paralysis in one or more limbs following an asthma attack. The paralysis is typically flaccid (weak and floppy) and is accompanied by muscle wasting and the loss of reflexes in the affected limb(s). The syndrome is named after Dr. John Hopkins, who first described it in 1976.

Symptoms[edit | edit source]

The primary symptom of Hopkins Syndrome is the sudden onset of paralysis in one or more limbs following an asthma attack. This paralysis is typically flaccid, meaning the muscles are weak and floppy. Other symptoms may include muscle wasting and the loss of reflexes in the affected limb(s).

Causes[edit | edit source]

The exact cause of Hopkins Syndrome is unknown. However, it is believed to be related to the immune response following an asthma attack. Some researchers believe that the immune system may mistakenly attack the nerves in the limbs, leading to paralysis.

Diagnosis[edit | edit source]

Diagnosis of Hopkins Syndrome is based on the presence of the characteristic symptoms following an asthma attack. There are no specific tests for the syndrome, but a doctor may use nerve conduction studies or electromyography to confirm the diagnosis.

Treatment[edit | edit source]

There is no cure for Hopkins Syndrome, and treatment is focused on managing the symptoms. This may include physical therapy to improve muscle strength and mobility, and medications to manage pain and other symptoms.

Prognosis[edit | edit source]

The prognosis for individuals with Hopkins Syndrome varies. Some individuals may experience a complete recovery, while others may have permanent paralysis. The severity of the paralysis and the individual's response to treatment can both affect the prognosis.

See also[edit | edit source]

Hopkins syndrome Resources
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Contributors: Prab R. Tumpati, MD