Human blood group systems
Human blood group systems are the classification of human blood based on the presence or absence of antigens on the surface of red blood cells. These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system.
Overview[edit | edit source]
The human blood group systems are primarily determined by genes inherited from one's parents. There are 36 recognized human blood group systems, including the ABO, Rh, and MNS systems. These systems play a crucial role in blood transfusion and organ transplantation.
ABO Blood Group System[edit | edit source]
The ABO blood group system is the most important blood group system in human blood transfusion. The associated anti-A and anti-B antibodies are usually IgM type, which are usually produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses.
Rh Blood Group System[edit | edit source]
The Rh blood group system (Rh meaning Rhesus) is the second most significant blood group system in human blood transfusion with currently 50 antigens. The most significant Rh antigen is the D antigen, because it is the most likely to provoke an immune system response of the five main Rh antigens.
MNS Blood Group System[edit | edit source]
The MNS blood group system is named after the first two antigens discovered, M and N. It is the third most significant system and has 46 antigens.
Other Blood Group Systems[edit | edit source]
Other blood group systems include the Kell blood group system, Duffy blood group system, Kidd blood group system, and Lutheran blood group system, among others. Each of these systems has its own set of antigens that can provoke an immune response if transfused into a person who lacks the antigen.
Importance in Transfusion Medicine[edit | edit source]
The human blood group systems are of critical importance in transfusion medicine. Mismatched blood transfusions can lead to severe immune reactions, potentially leading to transfusion reactions or hemolytic disease of the newborn.
See Also[edit | edit source]
| Human blood group systems Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
