Hypopyon

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An accumulation of pus in the anterior chamber of the eye



Hypopyon[edit | edit source]

A clinical image showing hypopyon in the anterior chamber of the eye.

A hypopyon is an accumulation of pus in the anterior chamber of the eye. It is a clinical sign that indicates the presence of inflammation within the eye, often due to an infection or other inflammatory processes. The pus is composed of white blood cells, fibrin, and other inflammatory debris.

Causes[edit | edit source]

Hypopyon can be caused by a variety of conditions, including:

  • Endophthalmitis: A severe inflammation of the interior of the eye, often due to infection following surgery or trauma.
  • Uveitis: Inflammation of the uvea, which can be due to infectious or non-infectious causes.
  • Keratitis: Inflammation of the cornea, which can lead to hypopyon if severe.
  • Behçet's disease: A systemic inflammatory disorder that can affect the eyes.

Symptoms[edit | edit source]

Patients with hypopyon may experience:

Diagnosis[edit | edit source]

The diagnosis of hypopyon is primarily clinical, based on the observation of pus in the anterior chamber. Additional tests may include:

  • Slit lamp examination: To assess the extent of inflammation and check for other signs of eye disease.
  • Ultrasound: To evaluate the posterior segment of the eye if the view is obscured.
  • Culture and sensitivity tests: To identify infectious organisms if an infection is suspected.

Treatment[edit | edit source]

The treatment of hypopyon depends on the underlying cause:

  • For infectious causes, antibiotics or antifungal medications may be administered.
  • For inflammatory causes, corticosteroids or other anti-inflammatory medications may be used.
  • In some cases, surgical intervention may be necessary to address the underlying issue.

Prognosis[edit | edit source]

The prognosis for hypopyon varies depending on the cause and the timeliness of treatment. Prompt and appropriate management of the underlying condition can lead to a good outcome, while delayed treatment may result in complications such as vision loss.

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Contributors: Prab R. Tumpati, MD