IL-5
IL-5 is a type of interleukin that is produced by T helper cells and mast cells. It plays a crucial role in stimulating B cell growth and increasing eosinophil activity.
Function[edit | edit source]
IL-5 is primarily involved in the stimulation of B cell growth and the increase in eosinophil activity. It is produced by T helper cells in response to antigen stimulation. IL-5 also stimulates the production of immunoglobulin in B cells and promotes the differentiation of eosinophil precursors into mature eosinophils.
Role in Disease[edit | edit source]
Abnormal levels of IL-5 have been associated with various diseases. High levels of IL-5 are often found in patients with asthma and other allergic diseases. It is also involved in the pathogenesis of eosinophilic esophagitis, a chronic immune system disease.
Therapeutic Use[edit | edit source]
Several drugs that target IL-5 have been developed for the treatment of asthma and other allergic diseases. These include mepolizumab, reslizumab, and benralizumab. These drugs work by blocking the action of IL-5, thereby reducing the number of eosinophils in the blood.
See Also[edit | edit source]
- Interleukin
- T helper cell
- Mast cell
- B cell
- Eosinophil
- Immunoglobulin
- Asthma
- Allergic diseases
- Eosinophilic esophagitis
- Mepolizumab
- Reslizumab
- Benralizumab
| IL-5 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
