IRAK1
IRAK1 or Interleukin-1 receptor-associated kinase 1 is a protein that in humans is encoded by the IRAK1 gene. It is a member of the Interleukin-1 receptor-associated kinases family, which is a group of enzymes that play a key role in the innate immune response to bacteria.
Function[edit | edit source]
IRAK1 is a serine/threonine-protein kinase that plays a critical role in initiating immune response against foreign pathogens. It acts as a mediator of Toll-like receptor and Interleukin-1 receptor signaling pathways, which are necessary for immune response activation.
Clinical significance[edit | edit source]
Mutations in the IRAK1 gene have been associated with autoimmune diseases such as Systemic lupus erythematosus and rheumatoid arthritis. In addition, IRAK1 has been implicated in the development of cancer, particularly breast cancer and leukemia.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
| IRAK1 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
