Ibopamine
| Ibopamine | |
|---|---|
| Ibopamine.svg | |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
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| Legal status | |
| CAS Number | |
| PubChem | 1972 |
| DrugBank | DB08982 |
| ChemSpider | 1900 |
| KEGG | D04499 |
Ibopamine is a synthetic drug used primarily in the field of ophthalmology. It is a prodrug of epinine, which is a dopamine derivative. Ibopamine is used to induce mydriasis (dilation of the pupil) and is often employed in diagnostic procedures to evaluate intraocular pressure and other conditions of the eye.
Pharmacology[edit]
Ibopamine works by stimulating dopamine receptors in the eye, leading to the dilation of the pupil. This effect is useful in various diagnostic procedures, including the assessment of glaucoma and other ocular hypertension conditions. The drug is metabolized into epinine, which then exerts its pharmacological effects.
Clinical Uses[edit]
Ibopamine is primarily used in ophthalmic diagnostics. It is particularly useful in:
- Inducing mydriasis for fundus examination
- Evaluating intraocular pressure in patients suspected of having glaucoma
- Assessing the functionality of the anterior segment of the eye
Administration[edit]
Ibopamine is typically administered in the form of eye drops. The dosage and frequency depend on the specific diagnostic requirement and the patient's condition.
Side Effects[edit]
Common side effects of ibopamine include:
- Temporary blurred vision
- Mild eye irritation
- Increased intraocular pressure
Patients with a history of cardiovascular disease or hypertension should use ibopamine with caution, as it may exacerbate these conditions.
Contraindications[edit]
Ibopamine is contraindicated in patients with:
- Known hypersensitivity to the drug or its components
- Narrow-angle glaucoma
See Also[edit]
References[edit]
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