Ibopamine

Ibopamine is a glaucoma medication that was first introduced in the 1980s. It is a prodrug that is converted into epinine in the body, which acts as an adrenergic agonist to increase the outflow of aqueous humor and reduce intraocular pressure.

History[edit | edit source]

Ibopamine was first synthesized in the 1980s as a potential treatment for congestive heart failure. However, it was later found to be effective in treating glaucoma and has since been used primarily for this purpose.

Pharmacology[edit | edit source]

Ibopamine is a prodrug that is metabolized into epinine in the body. Epinine is an adrenergic agonist that stimulates the alpha-1 adrenergic receptor and beta adrenergic receptor, leading to an increase in the outflow of aqueous humor and a reduction in intraocular pressure.

Clinical use[edit | edit source]

Ibopamine is used in the treatment of glaucoma to reduce intraocular pressure. It is typically administered as eye drops.

Side effects[edit | edit source]

Common side effects of ibopamine include blurred vision, eye pain, and eye redness. In rare cases, it can cause systemic side effects such as hypertension, tachycardia, and palpitations.

See also[edit | edit source]

Ibopamine Resources
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