Icaridin

From WikiMD's Wellness Encyclopedia

Icaridin, also known as Picaridin or by its chemical name hydroxyethyl isobutyl piperidine carboxylate, is a synthetic compound commonly used as an insect repellent. It was developed by the German company Bayer AG in the 1980s and has since become a popular alternative to DEET (N,N-Diethyl-meta-toluamide), offering comparable protection against a variety of insects such as mosquitoes, ticks, and fleas without the skin irritation or plastic-damaging properties associated with DEET.

Chemistry[edit | edit source]

Icaridin is a colorless and odorless liquid at room temperature. Chemically, it is classified as a piperidine derivative, and its molecular formula is C12H23NO3. Its mode of action involves disrupting the olfactory senses of insects, effectively making the person wearing it less detectable to biting insects.

Efficacy[edit | edit source]

Studies have shown that Icaridin is effective in repelling various biting insects and ticks, making it a valuable tool in preventing insect-borne diseases such as malaria, dengue fever, Lyme disease, and Zika. Concentrations of Icaridin in repellent products typically range from 10% to 20%, which are effective for several hours depending on the formulation and the species of insect.

Safety[edit | edit source]

Icaridin is considered safe for use by humans when used as directed. It has been evaluated by the World Health Organization (WHO) and the Environmental Protection Agency (EPA) in the United States, both of which have concluded that Icaridin does not pose significant health risks. It is less irritating to the skin than DEET and can be used on children as young as two months old, according to the American Academy of Pediatrics.

Environmental Impact[edit | edit source]

Compared to DEET, Icaridin has a lower potential for environmental impact. It is not considered to be a significant risk to wildlife or water systems, partly because it is used in lower concentrations and is less volatile.

Usage[edit | edit source]

Icaridin can be found in various forms, including sprays, lotions, and wipes, making it versatile for different situations and preferences. For optimal protection, it should be applied to exposed skin and clothing according to the product's instructions. Reapplication times vary depending on the concentration of Icaridin and the type of insect repelling activity needed.

Regulation[edit | edit source]

The availability and regulation of Icaridin-containing products vary by country. In the United States, the EPA regulates insect repellents and has approved Icaridin as a safe and effective ingredient. In the European Union, products containing Icaridin are also approved and regulated for consumer use.

Conclusion[edit | edit source]

Icaridin is a safe and effective insect repellent that offers a good alternative to DEET. Its efficacy against a wide range of biting insects, coupled with its favorable safety profile, makes it a preferred choice for many individuals seeking protection from insect-borne diseases.


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Contributors: Prab R. Tumpati, MD