Ictal bradycardia

Icosapent Ethyl is a type of polyunsaturated fatty acid (PUFA) that is used as a medication to lower triglyceride levels. It is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA).

Pharmacology

Icosapent Ethyl is metabolized to EPA in the body. EPA has several effects that help to lower triglyceride levels. It reduces the production of triglycerides in the liver, increases the clearance of triglycerides from the blood, and has anti-inflammatory effects.

Clinical Use

Icosapent Ethyl is used to treat high triglyceride levels (hypertriglyceridemia). It is used in combination with diet and exercise in adults with triglyceride levels above 500 mg/dL. It is also used to reduce the risk of cardiovascular events in adults with elevated triglyceride levels and established cardiovascular disease or diabetes mellitus and two or more additional risk factors for cardiovascular disease.

Side Effects

The most common side effects of Icosapent Ethyl are gastrointestinal, including diarrhea, nausea, and abdominal pain. Other side effects can include joint pain, rash, and an increased risk of bleeding.

Interactions

Icosapent Ethyl can interact with other medications, including anticoagulants and antiplatelet drugs. It can increase the risk of bleeding when used with these medications.

Dosage

The usual dosage of Icosapent Ethyl is 2 grams twice daily with food.

See Also

• Omega-3 fatty acid
• Triglycerides
• Hypertriglyceridemia
• Cardiovascular disease
• Diabetes mellitus

This cardiovascular disease related article is a stub.