Ilaprazole
Overview of the proton pump inhibitor Ilaprazole
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Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production. It is known for its long-lasting effect and is used in various countries for managing acid-related disorders.
Mechanism of Action[edit | edit source]
Ilaprazole works by inhibiting the H+/K+ ATPase enzyme system, also known as the proton pump, in the parietal cells of the stomach lining. This inhibition prevents the final step of acid production, thereby reducing gastric acidity.
Pharmacokinetics[edit | edit source]
Ilaprazole is absorbed in the small intestine and undergoes hepatic metabolism primarily via the cytochrome P450 enzyme system. It has a longer half-life compared to other PPIs, which contributes to its prolonged action.
Clinical Uses[edit | edit source]
Ilaprazole is primarily used for:
Side Effects[edit | edit source]
Common side effects of Ilaprazole include:
Comparison with Other PPIs[edit | edit source]
Ilaprazole is often compared with other PPIs such as omeprazole, lansoprazole, and pantoprazole. It is noted for its longer duration of action and potentially fewer drug interactions.
Related pages[edit | edit source]
Ilaprazole chemical structure
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