Immethridine

Immethridine

Immethridine is a synthetic compound that belongs to the class of anticholinergic drugs. It acts as a muscarinic receptor antagonist, specifically targeting the M2 and M3 receptors. This pharmacological action results in the inhibition of acetylcholine binding to these receptors, leading to a decrease in cholinergic activity.

Mechanism of Action

Immethridine exerts its effects by competitively binding to the muscarinic receptors, thereby blocking the action of acetylcholine. By inhibiting the parasympathetic nervous system, it produces various physiological responses in the body.

Medical Uses

Immethridine is primarily used in the treatment of conditions that involve excessive cholinergic activity, such as overactive bladder and gastrointestinal disorders. It helps alleviate symptoms such as urinary frequency, urgency, and incontinence by reducing the contractions of the bladder muscles.

Side Effects

Common side effects associated with immethridine include dry mouth, constipation, blurred vision, and urinary retention. In some cases, it may also cause dizziness, confusion, and increased heart rate. Patients should be monitored for these adverse effects during treatment.

Contraindications

Immethridine is contraindicated in individuals with a known hypersensitivity to the drug or other anticholinergic agents. It should be used with caution in elderly patients and those with certain medical conditions, such as glaucoma, prostatic hypertrophy, and gastrointestinal obstruction.

Interactions

Caution should be exercised when combining immethridine with other medications that have anticholinergic properties, as this may potentiate the side effects of both drugs. Additionally, drugs that affect the QT interval or central nervous system function may interact with immethridine.

Dosage and Administration

The dosage of immethridine varies depending on the specific condition being treated and the patient's individual response to the medication. It is typically administered orally in the form of tablets or capsules. Patients should follow the prescribed dosing schedule and consult their healthcare provider for any dosage adjustments.

References

• Muscarinic receptor
• Acetylcholine
• Overactive bladder
• Anticholinergic drugs