In-Methylcyclophane

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In-Methylcyclophane is a type of cyclophane that is characterized by the presence of a methyl group attached to the indium atom in the cyclophane ring. This unique structure gives In-Methylcyclophane distinct chemical properties and potential applications in various fields such as organic chemistry, medicinal chemistry, and material science.

Structure and Properties[edit | edit source]

In-Methylcyclophane consists of a cyclophane ring, which is a hydrocarbon ring composed of carbon and hydrogen atoms. The distinguishing feature of this compound is the presence of a methyl group (-CH3) attached to an indium atom within the ring. This results in a unique three-dimensional structure that imparts specific chemical properties to the compound.

The presence of the indium atom in the cyclophane ring makes In-Methylcyclophane a potential candidate for use in catalysis. Indium is known for its ability to act as a Lewis acid, which can facilitate various chemical reactions.

Synthesis[edit | edit source]

The synthesis of In-Methylcyclophane involves the reaction of a cyclophane precursor with an indium compound, typically indium(III) chloride, in the presence of a methylating agent such as methyl iodide. The reaction proceeds via a nucleophilic substitution mechanism, resulting in the formation of the In-Methylcyclophane product.

Applications[edit | edit source]

Due to its unique structure and properties, In-Methylcyclophane has potential applications in various fields. In organic chemistry, it can be used as a catalyst for various types of reactions, including cross-coupling reactions and ring-opening reactions. In medicinal chemistry, it could potentially be used in the synthesis of new drugs. In material science, it could be used in the development of new materials with unique properties.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD