Indopanolol

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== Indopanolol ==

Indopanolol is a beta-adrenergic antagonist (commonly known as a beta blocker), which is a class of medications that are primarily used to manage cardiovascular diseases. Beta blockers work by blocking the effects of the hormone epinephrine, also known as adrenaline, and slowing the heart's rate, which helps to reduce blood pressure.

Mechanism of Action[edit | edit source]

Indopanolol, like other beta blockers, binds to beta-adrenergic receptors in the heart and blood vessels. This action inhibits the normal sympathetic nervous system response, which is responsible for the "fight or flight" response. By blocking these receptors, indopanolol reduces heart rate, decreases cardiac output, and lowers blood pressure.

Medical Uses[edit | edit source]

Indopanolol is used in the treatment of several cardiovascular conditions, including:

It may also be used in the management of other conditions such as migraine prophylaxis and anxiety.

Side Effects[edit | edit source]

Common side effects of indopanolol include:

Less common but more serious side effects can include:

Contraindications[edit | edit source]

Indopanolol should not be used in patients with:

Pharmacokinetics[edit | edit source]

Indopanolol is typically administered orally and is well absorbed from the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily via the kidneys. The half-life of indopanolol allows for once or twice daily dosing, depending on the specific formulation and patient needs.

History[edit | edit source]

Indopanolol was developed in the late 20th century as part of the ongoing research into beta blockers. It was designed to provide effective management of cardiovascular conditions with a favorable side effect profile.

See Also[edit | edit source]


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