Flurazepam

From WikiMD's WELLNESSPEDIA

(Redirected from Insumin)

Information about Flurazepam[edit]

Flurazepam is an orally available benzodiazepine used for therapy of insomnia. 


Liver safety of Flurazepam[edit]

As with most benzodiazepines, flurazepam therapy has not been associated with serum aminotransferase or alkaline phosphatase elevations; clinically apparent liver injury from flurazepam has been reported, but is very rare.


Mechanism of action of Flurazepam[edit]

Flurazepam (flur az' e pam) is a benzodiazepine used as a sleeping aid in the therapy of insomnia.  The sedating and soporific activity of the benzodiazepines is mediated by their ability to enhance gamma-aminobutyric acid (GABA) mediated inhibition of synaptic transmission through binding to the GABA-A receptor. 

FDA approval information for Flurazepam[edit]

Flurazepam was approved in the United States in 1970 for the short term management of insomnia.  For many years flurazepam was one of the most prescribed medications for sleep.  Currently, it is less commonly used, having been replaced by benzodiazepines and benzodiazepine analogues with shorter half-life and better tolerance.  Flurazepam is available in multiple generic forms and formerly under the brand name of Dalmane in capsules of 15 and 30 mg.  The recommended dose for adults is 15 to 30 mg shortly before bedtime.  Chronic use is often followed by tolerance and decrease in effectiveness. 

Side effects of Flurazepam[edit]

The most common side effects of flurazepam are dose related and include daytime drowsiness, lethargy, and dizziness.  Flurazepam and other benzodiazepines are classified as schedule IV controlled substances, indicating that they are capable of causing dependence, tolerance and abuse.

Benzodiazipines[edit]

Anticonvulsants Drugs[edit]

Anticonvulsants, and Benzodiazepines]

Sponsored Health Resource

W8MD weight loss success

W8MD Weight Loss, Sleep & MedSpa

Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.

GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.

Book a W8MD appointment · View GLP-1 specials

Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.

Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Retrieved from "https://wikimd.org/index.php?title=Flurazepam&oldid=6313823"