Interleukin 1 receptor-like 1
Interleukin 1 receptor-like 1 (also known as IL1RL1) is a protein that in humans is encoded by the IL1RL1 gene. It is a member of the Interleukin-1 receptor family and is involved in the process of inflammation and immune responses.
Function[edit | edit source]
The protein encoded by the IL1RL1 gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related structurally to the interleukin 1 receptor accessory protein. The function of IL1RL1 is not known. However, it is thought to be involved in many immune responses.
Clinical significance[edit | edit source]
Alterations in the function of IL1RL1 may be involved in the pathogenesis of various diseases, including asthma, eczema, and allergic rhinitis. Studies have also suggested a role for IL1RL1 in the development of autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus.
Interactions[edit | edit source]
IL1RL1 has been shown to interact with MYD88, a universal adapter protein that is an essential component of the Toll-like receptor and IL-1 receptor signaling pathways.
See also[edit | edit source]
References[edit | edit source]
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