Interleukin 26
Interleukin 26 (IL-26) is a cytokine that is part of the interleukin family, specifically the IL-10 subfamily. It is encoded by the IL26 gene in humans and is involved in inflammatory and immune responses.
Function[edit | edit source]
IL-26 is produced by T cells, particularly Th17 cells, in response to infection or inflammation. It acts on various cell types, including epithelial cells, endothelial cells, and monocytes, to induce the production of pro-inflammatory cytokines and chemokines. This leads to the recruitment and activation of neutrophils, enhancing the immune response.
Role in Disease[edit | edit source]
IL-26 has been implicated in several diseases, including rheumatoid arthritis, psoriasis, and inflammatory bowel disease. It is thought to contribute to the pathogenesis of these diseases by promoting inflammation and tissue damage.
Therapeutic Potential[edit | edit source]
Due to its role in inflammation and immune responses, IL-26 is being investigated as a potential therapeutic target for inflammatory and autoimmune diseases. Inhibiting IL-26 activity could potentially reduce inflammation and tissue damage in these conditions.
See Also[edit | edit source]
 | This immunology article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
