Interpeduncular cistern

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Gray768

Interpeduncular cistern is a significant anatomical structure in the human brain, located at the base of the brain, between the two cerebral peduncles of the midbrain. It is part of the subarachnoid space, which is filled with cerebrospinal fluid (CSF). The interpeduncular cistern is an important area for the circulation of CSF, which provides a cushioning effect for the brain, offers buoyancy, and removes waste products.

Anatomy[edit | edit source]

The interpeduncular cistern is bordered anteriorly by the mammillary bodies of the hypothalamus, posteriorly by the pons, and inferiorly by the upper surface of the cerebellum. It encloses several important structures, including the basilar artery, the circle of Willis, and the origins of several cranial nerves. The cistern is named for its location, nestled between the cerebral peduncles, which are two large bundles of fibers that connect the forebrain to the hindbrain.

Function[edit | edit source]

The primary function of the interpeduncular cistern, as with other cisterns within the brain, is to act as a reservoir for cerebrospinal fluid. This fluid circulates through the ventricular system of the brain and the subarachnoid space, providing a protective cushioning for the brain, maintaining intracranial pressure, and facilitating the removal of metabolic waste products. The CSF also plays a crucial role in brain homeostasis and in providing a stable environment for the central nervous system.

Clinical Significance[edit | edit source]

The interpeduncular cistern is of particular interest in clinical medicine due to its location and the vital structures it contains. Pathological conditions such as subarachnoid hemorrhage, meningitis, and tumors can affect this area, leading to a variety of neurological symptoms depending on the structures involved. Imaging studies, such as MRI and CT scans, often focus on the interpeduncular cistern when diagnosing conditions related to the brainstem and surrounding areas.

Imaging[edit | edit source]

In neuroimaging, the interpeduncular cistern is a critical landmark. It is visible in both CT scans and MRI, providing valuable information about the brain's basal cisterns and the flow of cerebrospinal fluid. Abnormalities in the size or shape of the interpeduncular cistern, or the presence of lesions within it, can be indicative of underlying pathology.

Conclusion[edit | edit source]

The interpeduncular cistern plays a crucial role in the protection and functioning of the brain. Understanding its anatomy and function is essential for diagnosing and treating neurological conditions that affect the brainstem and surrounding regions.


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Contributors: Prab R. Tumpati, MD