Ipamorelin
Overview[edit | edit source]
Ipamorelin is a synthetic peptide that functions as a growth hormone secretagogue. It is part of a class of compounds known as growth hormone releasing peptides (GHRPs), which stimulate the release of growth hormone (GH) from the anterior pituitary gland. Ipamorelin is known for its selectivity and potency, making it a subject of interest in both clinical and research settings.
Mechanism of Action[edit | edit source]
Ipamorelin works by mimicking the action of the natural hormone ghrelin, which binds to the growth hormone secretagogue receptor (GHSR) in the brain. This binding stimulates the pituitary gland to release growth hormone. Unlike some other GHRPs, Ipamorelin does not significantly affect the levels of other hormones such as cortisol or prolactin, which contributes to its favorable side effect profile.
Clinical Applications[edit | edit source]
Ipamorelin is primarily used in research settings to study its effects on growth hormone release and its potential therapeutic applications. It has been investigated for its potential to:
- Promote muscle growth and fat loss
- Improve bone density
- Enhance recovery from injuries
- Support anti-aging therapies
Pharmacokinetics[edit | edit source]
Ipamorelin is typically administered via subcutaneous injection. It has a rapid onset of action, with growth hormone levels peaking within 15 to 30 minutes after administration. The half-life of Ipamorelin is approximately 2 hours, which allows for multiple daily dosing if necessary.
Safety and Side Effects[edit | edit source]
Ipamorelin is generally well-tolerated, with a low incidence of side effects. Commonly reported side effects include:
Due to its selective action, Ipamorelin does not significantly increase levels of cortisol or prolactin, reducing the risk of side effects associated with these hormones.
Research and Development[edit | edit source]
Research on Ipamorelin continues to explore its potential benefits and applications. Studies are ongoing to determine its efficacy in various clinical scenarios, including its role in muscle wasting conditions and age-related decline in growth hormone levels.
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