Iprazochrome
A drug used in the treatment of migraine and vascular headaches
| Iprazochrome | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Iprazochrome is a medication primarily used in the treatment of migraine and other types of vascular headaches. It belongs to the class of drugs known as serotonin receptor antagonists, which work by modulating the effects of serotonin in the brain.
Pharmacology[edit | edit source]
Iprazochrome is a derivative of ergot alkaloids, which are compounds derived from the Claviceps purpurea fungus. These compounds have a long history of use in the treatment of headaches due to their ability to constrict blood vessels and alter neurotransmitter activity.
Mechanism of Action[edit | edit source]
Iprazochrome acts as a serotonin receptor antagonist, specifically targeting the 5-HT2 receptors. By blocking these receptors, iprazochrome helps to prevent the excessive dilation of blood vessels in the brain, which is a common cause of migraine headaches.
Clinical Use[edit | edit source]
Iprazochrome is used in the prophylactic treatment of migraine headaches. It is not effective for the acute treatment of migraine attacks but is used to reduce the frequency and severity of these episodes.
Side Effects[edit | edit source]
Common side effects of iprazochrome include nausea, dizziness, and fatigue. In rare cases, it may cause more serious side effects such as allergic reactions or cardiovascular issues.
History[edit | edit source]
Iprazochrome was developed in the mid-20th century as part of efforts to find effective treatments for migraine headaches. Its development was based on the understanding of the role of serotonin in migraine pathophysiology.
Related pages[edit | edit source]
Iprazochrome[edit | edit source]
Iprazochrome
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
