Isonipecotic acid
Isonipecotic acid is an organic compound with the formula C6H11NO2. It is a carboxylic acid that contains a pyrrolidine ring, and is a structural isomer of nipecotic acid. Isonipecotic acid is used in the synthesis of various pharmaceuticals, including some antiepileptic drugs.
Structure and properties[edit | edit source]
Isonipecotic acid consists of a five-membered pyrrolidine ring, which contains a nitrogen atom, and a carboxylic acid group. The presence of the nitrogen atom makes the compound a heterocycle. The carboxylic acid group can participate in hydrogen bonding, which can affect the compound's physical properties and reactivity.
Synthesis[edit | edit source]
Isonipecotic acid can be synthesized from glutaric acid or its derivatives, in a process that involves the formation of a cyclic compound and subsequent functional group transformations.
Applications[edit | edit source]
Isonipecotic acid is used as a building block in the synthesis of various pharmaceuticals. For example, it is used in the synthesis of vigabatrin, an antiepileptic drug. The compound's pyrrolidine ring can act as a bioisostere for the GABA neurotransmitter, which can enhance the activity of GABA in the brain and help to control seizures.
Safety[edit | edit source]
As with all chemicals, isonipecotic acid should be handled with care. It can cause skin and eye irritation, and may be harmful if swallowed or inhaled.
See also[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
