Isopromethazine

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Isopromethazine is a pharmaceutical drug that belongs to the class of phenothiazine derivatives. It is primarily used as an antihistamine, which means it is effective in treating allergic reactions. It can also be used as a sedative, for its calming effects, and as an antiemetic, to prevent nausea and vomiting.

Pharmacology[edit | edit source]

Isopromethazine works by blocking the effects of histamine, a substance in the body that causes allergic symptoms. It also affects certain areas in the brain to produce a calming effect. As an antiemetic, it works by blocking the signals to the brain that cause nausea and vomiting.

Uses[edit | edit source]

Isopromethazine is used to treat a variety of conditions, including:

  • Allergic reactions: It can be used to treat symptoms of allergies, such as itching, runny nose, and watery eyes.
  • Sedation: It can be used to induce sleep or to calm patients before or after surgery.
  • Nausea and vomiting: It can be used to prevent and treat nausea and vomiting caused by motion sickness, anesthesia, and chemotherapy.

Side Effects[edit | edit source]

Like all medications, Isopromethazine can cause side effects. These may include drowsiness, dizziness, constipation, blurred vision, or dry mouth. In rare cases, it can cause serious side effects such as seizures, irregular heartbeat, and severe allergic reactions.

Precautions[edit | edit source]

Before using Isopromethazine, patients should inform their healthcare provider about any allergies, medical conditions, or other medications they are taking. It should be used with caution in patients with certain conditions such as glaucoma, heart disease, liver disease, and certain mental/mood conditions.

See Also[edit | edit source]

Isopromethazine Resources
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Contributors: Prab R. Tumpati, MD