Juvenile nasopharyngeal angiofibroma

Juvenile nasopharyngeal angiofibroma (JNA) is a rare, benign, vascular tumor that occurs in adolescent males. Despite its benign nature, it can cause severe morbidity and mortality due to its location and propensity for aggressive growth.

Epidemiology[edit | edit source]

JNA is most commonly diagnosed in adolescent males between the ages of 10 and 20. It accounts for 0.05% of all head and neck tumors.

Pathophysiology[edit | edit source]

The exact cause of JNA is unknown, but it is thought to originate from the sphenopalatine foramen. The tumor is composed of fibrous tissue and blood vessels.

Clinical Presentation[edit | edit source]

Patients with JNA typically present with unilateral nasal obstruction and recurrent epistaxis. Other symptoms can include headache, facial swelling, and visual disturbances.

Diagnosis[edit | edit source]

Diagnosis of JNA is typically made through a combination of clinical history, physical examination, and imaging studies. Computed tomography (CT) and magnetic resonance imaging (MRI) are commonly used to evaluate the extent of the tumor.

Treatment[edit | edit source]

Treatment of JNA typically involves surgical removal of the tumor. Preoperative embolization may be used to reduce blood loss during surgery. Radiation therapy may be used in cases where surgery is not possible or if the tumor recurs.

Prognosis[edit | edit source]

The prognosis for JNA is generally good, with a high rate of long-term survival. However, the tumor can cause significant morbidity due to its location and potential for aggressive growth.

References[edit | edit source]

Juvenile nasopharyngeal angiofibroma Resources
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