Ketobemidone

From WikiMD's Food, Medicine & Wellness Encyclopedia

Ketobemidone is a potent opioid analgesic drug, which is used primarily in the treatment of severe pain. It is a synthetic opioid that is chemically related to pethidine (meperidine). Ketobemidone is marketed throughout Europe, particularly in Denmark, Sweden and Norway.

Pharmacology[edit | edit source]

Ketobemidone acts as a strong analgesic, approximately five to seven times more potent than morphine. It is a kappa-opioid receptor agonist and a NMDA receptor antagonist, which makes it useful for certain types of pain, particularly neuropathic pain.

Side Effects[edit | edit source]

Like other opioids, ketobemidone can cause a range of side effects, including nausea, vomiting, itching, and respiratory depression. It can also cause dependence and withdrawal symptoms if used for extended periods.

History[edit | edit source]

Ketobemidone was first synthesized in the 1940s by the Danish pharmaceutical company A/S Ferrosan. It was introduced for medical use in 1942.

See Also[edit | edit source]

Ketobemidone Resources
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Contributors: Prab R. Tumpati, MD