Ketobemidone
Ketobemidone is a potent opioid analgesic drug, which is used primarily in the treatment of severe pain. It is a synthetic opioid that is chemically related to pethidine (meperidine). Ketobemidone is marketed throughout Europe, particularly in Denmark, Sweden and Norway.
Pharmacology[edit | edit source]
Ketobemidone acts as a strong analgesic, approximately five to seven times more potent than morphine. It is a kappa-opioid receptor agonist and a NMDA receptor antagonist, which makes it useful for certain types of pain, particularly neuropathic pain.
Side Effects[edit | edit source]
Like other opioids, ketobemidone can cause a range of side effects, including nausea, vomiting, itching, and respiratory depression. It can also cause dependence and withdrawal symptoms if used for extended periods.
History[edit | edit source]
Ketobemidone was first synthesized in the 1940s by the Danish pharmaceutical company A/S Ferrosan. It was introduced for medical use in 1942.
See Also[edit | edit source]
Ketobemidone Resources | ||
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