Koeppe's nodules

Koeppe's nodules are small, round, inflammatory nodules that are found on the iris of the eye. They are named after the German ophthalmologist Leopold Koeppe, who first described them. Koeppe's nodules are most commonly associated with uveitis, an inflammation of the uvea, the middle layer of the eye.

History[edit | edit source]

Leopold Koeppe (1889–1945) was a German ophthalmologist who specialized in the study of the eye's uvea. He first described the nodules that now bear his name in the early 20th century. Koeppe's work in ophthalmology was pioneering, and his contributions to the field are still recognized today.

Characteristics[edit | edit source]

Koeppe's nodules are small, round, inflammatory nodules that are found on the iris of the eye. They are typically less than 1 mm in diameter and are often multiple. The nodules are usually white or yellowish in color.

Causes[edit | edit source]

Koeppe's nodules are most commonly associated with uveitis, an inflammation of the uvea, the middle layer of the eye. They can also be seen in other inflammatory conditions of the eye, such as sarcoidosis and tuberculosis. In rare cases, they may be associated with systemic diseases like rheumatoid arthritis and lupus.

Diagnosis[edit | edit source]

The diagnosis of Koeppe's nodules is typically made by an ophthalmologist during a slit lamp examination of the eye. The nodules are visible on the iris and their presence can help confirm a diagnosis of uveitis or other inflammatory eye conditions.

Treatment[edit | edit source]

Treatment for Koeppe's nodules is aimed at treating the underlying cause of the inflammation. This may involve the use of anti-inflammatory medications, such as corticosteroids, or immunosuppressive drugs in cases where the inflammation is due to an autoimmune disease.