Koplik's Spots[edit | edit source]

Photograph of Koplik's spots in a patient with measles.

Koplik's spots are distinctive small red lesions with white or bluish centers, typically found on the mucous membranes inside the mouth and tongue. They are a hallmark symptom of measles and appear one to two days before the onset of the measles rash.

Identification[edit | edit source]

Koplik's spots are characterized by:

Small size, usually 1-2 mm in diameter
Red base with a central white or bluish speck
Location on the buccal mucosa opposite the lower molars

Association with Measles[edit | edit source]

Koplik's spots are considered pathognomonic for measles, meaning their presence is strongly indicative of the disease.
They appear during the prodromal phase of measles, making them an important diagnostic sign.

Diagnostic Significance[edit | edit source]

Early identification of Koplik's spots can lead to timely diagnosis of measles, which is critical for infection control.
They help distinguish measles from other febrile rash illnesses.

Differential Diagnosis[edit | edit source]

Koplik's spots should be differentiated from other oral lesions, such as:

Herpangina
Hand, foot, and mouth disease
Aphthous ulcers

External Links[edit | edit source]

Koplik's spots Resources
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