Lübeck vaccine disaster

Lübeck Vaccine Disaster

The Lübeck Vaccine Disaster was a significant event in the history of vaccination, which occurred in Lübeck, Germany in 1930. This incident involved the administration of tuberculosis (TB) vaccine to infants, which resulted in the death of 72 children and caused serious illness in many others.

Background

In the early 20th century, tuberculosis was a major public health concern worldwide. The development of the BCG vaccine by Albert Calmette and Camille Guérin offered hope for the prevention of the disease. However, the Lübeck disaster highlighted the risks associated with vaccine production and administration.

The Disaster

In 1930, the city of Lübeck initiated a program to vaccinate newborns against tuberculosis using the BCG vaccine. However, due to a tragic error in the preparation of the vaccine, a batch was contaminated with a virulent strain of Mycobacterium tuberculosis, the bacterium that causes TB. As a result, 251 infants were infected, of whom 72 died.

Aftermath and Impact

The Lübeck Vaccine Disaster had far-reaching consequences. It led to a loss of public confidence in vaccines and a temporary halt in BCG vaccination in many countries. It also highlighted the need for stringent controls in vaccine production and administration.

The disaster led to significant changes in the field of vaccinology. It underscored the importance of rigorous testing and quality control in vaccine production. It also highlighted the need for careful monitoring of vaccination programs and the importance of public communication in maintaining trust in vaccines.

See Also

• History of tuberculosis
• BCG vaccine
• Vaccine controversy
• Vaccine safety